Inane Arguments – Not Helpful

I was gonna do a quasi truthful rundown on j’ames’s’z unspoken request for real information on luciferase…

Instead I’m just gonna say Calm down Mare!

Leon beat me to the punch –

So I guess there is no sense in saying:

Bioluminescence is naturally occurring.

Seen in many living organisms.

It has been observed for thousands of years.

Aristotle (384-322 BCE) was fascinated by it.

Pliny the Elder (23-79 CE) reported bioluminescence recording descriptions of numerous glowing organisms. See his rundown in Playboy’s ’79 best of edition titled: Historia Naturalis.

In 1667, it was discovered by Robert Boyle that bio-luminescence required air.

Chucky D called the process phosphorescence while smoking weed aboard the Beagle.

More recently, Luciferase has been isolated from various beasties and has become indispensable in shedding light on innumerable tiny puzzles.

It can be used to great effect in figuring out:

  • protein to protein interactions
  • gene regulation and cell signalling
  • tracking protein stability under different environments
  • creating biosensors

We literally take these molecules and stick them to areas of other molecules (like proteins) and are then able to watch movement at a molecular level.

Some of the neat stuff coming out of bio-luminescence research is the ability to detect the VERY early stages of infection of nasty diseases like HIV. By getting a jump on knowing infection status with viruses early, we are able to start treatment at a stage where it is possible to eradicate the disease before it takes hold in the host.

BUT – seeing as how leon already answered jay’s quasi-missive I wont bother to chime in.

Instead Lets Talk About :



  1. Instead, the first true hermits were priapulids—suggestively shaped critters known as penis worms,

    “They’re a neat group of animals with an unfortunate name,” study co-author Martin Smith, a paleontologist at the University of Durham
    Suggestive and unfortunate are adjectives that are inappropriately used for the penis worm. We need to have PENIS PRIDE !!!

  2. The ideal shell for a penis worm is not found in nature

  3. Cambrian Explosion indeed

  4. “It might as well be called the Strategic Political Reserve.

    After the OPEC+ cartel rebuffed President Biden’s request to release more oil last Thursday, the White House floated the idea of releasing barrels from the Strategic Petroleum Reserve to tame prices.”

    From a WSJ article about Poopy Pants Biden’s potential response to rising oil prices. What a maroon.

  5. My local grocery store has a promo of 10% off your bill on Veteran’s Day. I can’t think of anything I need today so I’ll pass. Out of curiosity I looked at the frozen turkeys earlier this week and they were a. plentiful and b. roughly $20-25 apiece for a large turkey. I know the free range birds the co op was advertising were much more expensive, $6.99/pound. I’ve had those before and they are super good, just too pricey this year. We’ll stick with the bowling ball version this time around.

  6. Wakey wakey

  7. Carin, what park are you exploring today?

  8. I always do the bowling ball variety. I’m cheap, and they are pre brined

  9. *puts the tin foil on

    /Hansen brother

  10. VMax, these are the best gas cans we’ve found:


  12. Disney MGM

  13. How has the weather been for you?

  14. *wonders why jay has his junk wrapped in tin foil*

  15. Comment by jam2 on November 11, 2021 8:32 am
    *wonders why jay has his junk wrapped in tin foil*



  16. It’s been ok. It rained yesterday. A lot.

  17. I’m not sure who first mentioned it, but I started watching Band of Brothers a few weeks back and finally got the part where they drop into Normandy.

    That’s one of the best things I’ve ever seen anywhere, period. I was unbelievably anxious and couldn’t stop watching.

  18. we protect that which is most valuable to us, jamster

  19. I think Saving Private Ryan landing at Normandy was more intense, but Band Of Brothers was certainly exciting. Better on the whole, anyway.

  20. Hotspur mentioned it and pretty much everyone piled on to say how great of a series it was except you. Velcome to the party.

    TCM is doing a full day of war type movies BTW. I looked at the schedule and it seemed more like military related was a better description. Not many war war movies IYKWIM

  21. I’m not sure who first mentioned it, but I started watching Band of Brothers a few weeks back and finally got the part where they drop into Normandy.

    That was me. And it took you a few weeks to get to the Normandy drop?

    Dude, that’s episode 2.

    I like the way at the beginning of each episode have the vets tell some of their story.

    Undoubtedly every one of those guys is gone now.

  22. yes, I believe they are all gone now. Heard about Winters passing, and Guarnere wasn’t it? Lipton too.


    Yep, last one passed in 2019

  24. MJ hung out at AOS, that smart military blog, and hadn’t watched Band of Brothers yet? Turn off Legally Blonde!

  25. That was me. And it took you a few weeks to get to the Normandy drop?
    I have very little fuck off time. And I wanted to pay attention.

    Wow. The balls on those guys.

  26. Have you seen the Saving Private Ryan version? Better watch that too, Mr Research.

  27. Happy Veterans Day to all our Hostage veterans, thank you for your service!

  28. Don’t forget TCM is running GI Blues with Elvis later today

  29. Wow. The balls on those guys.

    It gets better and better. The Christmas they spent in the Ardennes is pretty intense.

  30. the prison camp scene still gets me

  31. anyone got a line to a mod at AOS? The top two links in the sidebar are fubared. Probably a closing tag. Right up until the Tucker Carlson link.

  32. the prison camp scene still gets me

    Let’s not spoil it for MJ

  33. no spoiling, but he HAD to hear about that, right?

    Oh right, never mind.

  34. Don’t think I’ve ever seen GI Blues. At least I don’t remember any of it.

  35. Old people yelling at clouds, today and every day at the H2

  36. Oopsie

  37. I walked to the Lincoln Memorial this morning and re-read these words:

    “Four score and seven years ago our fathers brought forth, on this continent, a new nation, conceived in Liberty, and dedicated to the proposition that all men are created equal.

    Now we are engaged in a great civil war, testing whether that nation, or any nation so conceived and so dedicated, can long endure. We are met on a great battle-field of that war. We have come to dedicate a portion of that field, as a final resting place for those who here gave their lives that that nation might live. It is altogether fitting and proper that we should do this.

    But, in a larger sense, we can not dedicate—we can not consecrate—we can not hallow—this ground. The brave men, living and dead, who struggled here, have consecrated it, far above our poor power to add or detract. The world will little note, nor long remember what we say here, but it can never forget what they did here. It is for us the living, rather, to be dedicated here to the unfinished work which they who fought here have thus far so nobly advanced. It is rather for us to be here dedicated to the great task remaining before us—that from these honored dead we take increased devotion to that cause for which they gave the last full measure of devotion—that we here highly resolve that these dead shall not have died in vain—that this nation, under God, shall have a new birth of freedom—and that government of the people, by the people, for the people, shall not perish from the earth.”


  39. amazing, imagine Brandon trying to give a speech like that.

  40. Happy Veterans Day H2. NC @ Pitt game tonight. I’ve never been in a city that has parades in pretty much every township and city. Not just chains, but local restaurants have deals for Vets. We used to have a Bataan Park gathering, but most, if not all Bataan veterans are dead. Sobek, Gettysburg Address Anniversary is next week.

  41. 7th Grade Social Studies we had to memorize and deliver The Gettysburg Address.

  42. Can you imagine a teacher requiring a student to memorize and deliver any of Poopy Pants Biden’s “speeches”?

  43. Imagine thinking that “God Bless America” was a politically divisive statement.

  44. there’s a lot of UM in there, which is a staple of public speaking classes.

  45. I made the mistake of watching Kyles testimony at Steve’s Snapping hot dogs in the Denver airport. We eat there every single time, while traveling through Denver. It was so busy, we couldn’t sit at our usual table. I was ugly crying while eating my Dallas Hotdog with a knife and fork. 🐻👋🏻🦎/🐊

  46. hahaha, were you wearing your tiara?

  47. I can’t think of a modern era speech by a President worth memorizing. Maybe, Reagan and Shining City on a Hill or Reagan Challenger Memorial Speech. Ws response on the bullhorn, wasn’t a speech. Pretty memorable response, though.

  48. Reagan at Point Du Hoc

  49. J’ames, my tiara didn’t make the cut. I did mix it up with a United mask Nazi before Dan calmed me down and pulled me away.

  50. Lincoln was a gay racist. Tear down the statue and put up a rainbow flag.

  51. J’ames, OMG How could I forget that amazing speech!

  52. MJ, he was married to a mentally unstable short woman, BIRM.

  53. listening to Crowder do his Gilbert Gottfried imitation sounds a lot like his Al Pacino imitation, but then it occurred to me how similar they are.

  54. Car in, BITD I researched Mission to Mars. Hard No. Dan had to ride it by himself. I sat on a bench nearby, and a Hong Kong Disney intern and I practiced Mandarin and English together. She laughed at my Taiwan accent.

  55. 7th Grade Social Studies we had to memorize and deliver The Gettysburg Address.

    Same here, but I can’t remember which grade.

  56. Gas is available in Socorro again. I can’t confirm that they were totally out yesterday, or if it was a “chicken little, the sky is falling rumor”. Several stations were out night before last. Definitely a wake up call.
    It’s amazing just how quickly things can deteriorate. I’m expecting random outages of things for the future. Gas, misc. food, parts, common stuff just won’t be available.

  57. We had to memorize the Gettysburg Address as well.

  58. We had to memorize your mom’s address which was pretty simple all things considered

  59. Appointment was a waste of time. Nothing accomplished but another appointment made to extract yet another co-pay. I’m about to give up on the whole deal.

  60. ask questions, Tim, about appointments. Don’t just take what they give. Justify the appointments. I’ve gotten out of followups by doing that, and a phone call is good enough. Sometimes they assume things.

  61. he wants to do another CT scan to establish whether the one stone has truly passed. (Since I wasn’t able to capture it there is legit doubt). The soonest followup appointment is end of December. No procedure would be able to take place in calendar 2021 under those conditions, which means my insurance resets. It’s pretty much my worst possible scenario and I told them such.

    They gave me papers for applying for some sort of charitable status. It’s fucking humiliating and I feel like I’m being farmed and condescended to. Must be what it’s like to be a Democrat minority.


    I checked it out (redballoon). Looks like I may be able to work in my chosen field… if we move to Kentucky.

  63. Upside: you’d get to vote for Rand Paul and whomever challenges Mitch.

  64. TN and KY are on my short list anyway. But we just can’t leave here yet, family keeping us here. I wonder how old I’ll be when we can finally move.


  66. In line for new Star Wars ride

  67. Victory Gardens, people. There is a massive shortage of nitrogen fertilizer coming down the pike. Farms and everything that depends on farm output is going to be high.

  68. My friend at work told me about the new Star Wars ride, it sounded pretty cool.

  69. I’ve, uh, got nitrogen covered.

    If I had two ewes, I’d be set for food.


    (Imgur video with sound)

  71. is that crab actually chasing the camera?

  72. Can we be sure that isn’t Richard Blumenthal?

  73. Heading back to DC tomorrow. Get in pretty early, may take a stroll around the mall.

  74. Oh. My. God.

  75. Here’s an anecdote about the mandate for EMS in Maine. I tried confirming it but came up empty.

    Paula saw a Facedouche post by our snowplow guy who is an EMT for our VFD in addition to his regular job. He gave his good-byes to the department last month because he wasn’t getting the jab. He posted today saying he was glad to be back. Said the mandate for EMS was rescinded. Same with dental offices.

    They must be feeling the shortages for that to happen. They are offering huge sign on bonuses to new and experienced nurses as well as loan repayment programs. They’ve suspended the distance requirement to be a traveling nurse just to get bodies to staff the wards. There are nurses making twice their usual salary working at a hospital across town from their usual place of employment.

  76. Did you make it CARin? I heard those Storm Troopers are dicks.

  77. I had In-N-Out today. Alas, no “Let’s Go Brandon” on the cup for me. Oh well. It’s 5 o’clock, let’s go Laiphroaig.

  78. Scott observes me eating potato chips.

    “What is your method for eating these chips? You’re sorting them.”

    Me: “I didn’t think about it until you asked me, but I eat all the tiny chippies first, keep searching for the next smallest, and ending with the biggest ones.”

    Scott: “the folded ones are the bes-

    Me: “YES. I ate the folded one last.”

    I need to figure out a method for frying potato chips so they all fold. I will become quadrillionairesse.

  79. People will become so addicted to folded chippies, most of the Earth’s acreage will be turned to Folded Chip Production. It won’t be a problem.

  80. Space-based potato farming is the next big thingtm. Imagine a giant toroid of spuds all growing at perfect, perpetual temperature, pressure, and “gravity”. Drop-shipped to the continent of your choice.



  83. Comment by leoncaruthers on November 11, 2021 8:40 pm
    Space-based potato farming is the next big thingtm. Imagine a giant toroid of spuds all growing at perfect, perpetual temperature, pressure, and “gravity”. Drop-shipped to the continent of your choice.

    *sees stars*

  84. Anyway. I have some home-saved seeds to share. Some in bulk, some in small quantities. I’m going to do a local swap thing and also giveaways. I will post here as the time arrives whatever food seeds I
    have to give. Love you. Start a compost pile if you haven’t already. We may all need a garden. or just buy a shittonne of good canned veggies and soups right now.

  85. hope you want to grow seven acres of parsnips

  86. because I have eighteen times that many seeds

  87. In other news, allow your best parsnips to overwinter and go to seed

  88. I don’t think I’ve ever eaten a parsnip in my life. I have no idea what I’d do with one, frankly.

    I’ve never been one for gardening and the like. My parents were back in the 80’s in California and I had to help. A LOT. After we moved away from there I dedicated my life to avoiding yard-work.

  89. Parsnips are wonderful. You do need a cold climate, though. Very sweet, herbal root vegetable. Similar to a carrot in shape but far, far, superior in flavor. They must be harvested after a few hard frosts and thereafter through the Winter, at every opportunity when the ground thaws. Because sugar is a natural antifreeze, they just keep improving. Last pullings are in Spring. If you are wise, you leave the biggest, best specimens to flower and make seed.

  90. The Interrogation was rough, pupster. Erin broke down (laughing) and my bil said he’d sell us all out.

  91. Yeah? Well lay some parsnip recipes on us there Root Wrangler.

  92. Parsnips are the older. more sophisticated cousin of the carrot.

    I don’t grow them or any roots at this point, because I use so much manure in my compost that I’m nervous about contamination, but they are good eating. Awesome in stews.

  93. I make a roasted root vegetable soup with carrots, onion, parsnips, small turnips roasted with olive oil, salt and pepper, then dumped into the soup pot with tomato sauce and beef broth.

    Which brings me to my stepmother not knowing the difference between broth and bouillon. Sigh.

  94. We left the game before the rain started. Watching from the comfort of our hotel room as our game goes into OT. I’ve been telling Dan about Market Price for wings FOR MONTHS. We went to Quaker State and Lube…$20 for 12 wings. Not as bad as Cali. Kira paid $25 for 6 wings.

  95. Declaring, “Egad!” Randolph perished.

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